Recently Arrived Indian Woman With Rare TB Triggers Health Scare In US

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WASHINGTON – An Indian woman with a rare drug-resistant form of tuberculosis has triggered a health scare in three US states and for co-passengers on her flight from India, as American authorities are tracking down hundreds of people who may have been in her contact.

The woman, who arrived in Chicago from India on April 4 and travelled by car to visit relatives in Illinois, Tennessee and Missouri, is now being treated at an isolated facility at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

She is suffering from an extremely rare drug-resistant form of the disease, known as XDR-TB, which is immune to most tuberculosis drugs, The New York Times reported.

The unidentified woman is in an isolation room designed for patients with dangerous respiratory infections, according to the National Institutes of Health and the Centers for Disease Control and Prevention (CDC). The CDC today described her condition as stable.

Health officials in Illinois were working with the CDC to find people with whom the woman may have had prolonged direct contact, in close quarters.

Health officials say the risk to the public is low. TB is nowhere near as contagious as the flu or measles. But people who had long periods of close contact with the patient, like the relatives with whom she stayed, are at risk.

For people who were on the flight with the woman, the odds of catching TB are low but not zero.

The CDC said that it will obtain the flight manifest for the woman’s trip from India and notify passengers who may have been exposed.

Based on her medical history and molecular testing, she was diagnosed with XDR TB, it reported.

She was initially placed in respiratory isolation at a suburban Chicago hospital and later transported by air ambulance to the NIH Clinical Center. — PTI

The woman is suffering from an extremely rare drug-resistant form of the disease, known as XDR-TB

What is XDR-TB?

XDR-TB, an abbreviation for extensively drug-resistant tuberculosis, is a form of TB which is resistant to at least four of the core anti-TB drugs. XDR-TB involves resistance to the two most powerful anti-TB drugs, isoniazid and rifampicin, also known as multidrug-resistance (MDR-TB), in addition to resistance to any of fluoroquinolones and to at least one of three injectable second-line drugs

Can XDR-TB be cured?

XDR-TB patients can be cured, but with the current drugs available, the likelihood of success is much smaller than in patients with ordinary TB or even MDR-TB. Cure depends on the extent of the drug resistance, the severity of the disease and whether the patient’s immune system is compromised. Effective treatment requires that a good selection of second-line drugs is available to clinicians